Effects of 10 years of growth hormone (GH) replacement therapy in adult GH-deficient men
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چکیده
منابع مشابه
Effects of 10 years of growth hormone (GH) replacement therapy in adult GH-deficient men.
OBJECTIVE GH-deficient adults have changes in body composition, bone mineral density (BMD) and lipid profile that can be altered by GH substitution. However, long-term data on GH substitution (up to 10 years of follow-up) are limited. DESIGN The effects of 10 years of GH replacement therapy on BMD, body composition, bone parameters, serum lipids and glucose metabolism were studied. PATIENTS...
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The long term effects of GH replacement in adult GH-deficient (GHD) patients have not yet been clarified. We studied 21 GHD adults who originally took part in a randomized, double blind, placebo-controlled trial of GH treatment in 1987. After completion of that trial, 10 patients received continuous GH replacement for the subsequent 10 yr, whereas 11 did not. A group of 11 age- and sex-matched ...
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ژورنال
عنوان ژورنال: Clinical Endocrinology
سال: 2005
ISSN: 0300-0664,1365-2265
DOI: 10.1111/j.1365-2265.2005.02343.x